Iron + Folic Acid + Zinc + Vitamin A + Vitamin C
Indications
Iron + Folic Acid + Zinc + Vitamin A + Vitamin C is used for:
Vitamin/mineral deficiency, Iron deficiency during pregnancy and lactation
Adult Dose
Once daily or as required.
Child Dose
Renal Dose
Administration
Contra Indications
Patients with a known hypersensitivity to any of the ingredients.
Precautions
Precautions should be exercised if hypersensitivity to any of its ingredients is manifested.
Pregnancy-Lactation
Interactions
Iron: Antacids may decrease the absorption of carbonyl iron.
Folic acid: Antiepileptics, oral contraceptives, anti-TB drugs, alcohol, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides may result to decrease in serum folate contrations. Decreases serum phenytoin concentrations.
Vit C: Deferroxamine, hormonal contraceptives, flufenazine, warfarin, elemental iron, salicylates, warfarin, fluphenazine, disulfiram, mexiletine, vitamin B12.
Adverse Effects
Side effects of Iron + Folic Acid + Zinc + Vitamin A + Vitamin C :
A few side-effects of oral iron preparations, including nausea, vomiting, constipation or diarrhoea may occur. Allergic sensitization has been reported following oral administration of folic acid.
Mechanism of Action
Iron: Essential component in the formation of hemoglobin; adequate amounts of iron are necessary for effective erythropoiesis; also serves as a cofactor of several essential enzymes, including cytochromes that are involved in electron transport. Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin.
Folic acid: Required for nucleoprotein synthesis and the maintenance of normal erythropoiesis; folic acid is converted in the liver and plasma to its metabolically active form, tetrahydrofolic acid, by dihydrofolate reductase; prevents neural tube defects in women of childbearing potential and higher doses required during pregnancy.
Zinc: Cofactor in over 100 enzymes; plays a role in DNA synthesis; supports a healthy immune system; helps maintain a sense of smell and taste; may assist in porper function of insulin.
Vitamin A plays an essential role in the function of retina and is essential for growh and differentiation of epithelial tissue.
Vitamin C is necessary for collagen formation and tissue repair; plays a role in oxidation/reduction reactions as well as other metabolic pathways including synthesis of catecholamines, carnitine, and steroids; also plays a role in conversion of folic acid to folinic acid.