Ketotifen Eye prep
Indications
Ketotifen Eye prep is used for:
Allergic conjunctivitis
Adult Dose
Ophthalmic
Allergic conjunctivitis
Adult: As 0.025% solution: Instill 1 drop into the affected eye(s) bid.
Child Dose
Ophthalmic
Allergic conjunctivitis
Adult: As 0.025% solution: Instill 1 drop into the affected eye(s) bid.
Child: >3 yr: As 0.025% solution: Instill 1 drop into the affected eye(s) bid.
Renal Dose
Administration
Contra Indications
Patients with known hypersensitivity to ketotifen or to any of the excipients of the preparation.
Precautions
Eye drops contains benzalkonium chloride as a preservative, which may be deposited in soft contact lenses; thereforeKetotifen eye drops should not be instilled while the patient is wearing contact lenses. The lenses should be removed before application of the drops and not reinserted earlier than 15 minutes after use.
Lactation: Not known if distributed in milk; use caution
Pregnancy-Lactation
Pregnancy Category: C
Lactation: Not known if distributed in milk; use caution
Interactions
Reduced platelet count with oral antidiabetics.
Potentially Fatal: May potentiate CNS effects of sedatives, hypnotics, antihistamines and alcohol.
Adverse Effects
Side effects of Ketotifen Eye prep :
Generally side effects of Ketotifen are localized ocular toxicity and hypersensitivity such as burning or stinging, punctate corneal epithelial erosion, dry eyes, eyelid disorder, photophobia, keratitis, lacrimation etc. Systemic side effects are very rare, there may be headache, urticaria, dry mouth and allergic reaction.
Mechanism of Action
Ketotifen selectively and noncompetitively inhibits the release of mediators from cells involved in hypersensitivity reactions. It is also a mast cell stabiliser.