Lodoxamide
Indications
Lodoxamide is used for:
Allergic conjunctivitis
Adult Dose
Ophthalmic
Allergic conjunctivitis
Adult: As 0.1% solution: 1-2 drops may be instilled into the affected eye(s) 4 times daily.
Child Dose
Ophthalmic
Allergic conjunctivitis
>2 years: 1-2 drops may be instilled into the affected eye(s) 4 times daily.
<2 years: safety and efficacy not established
Renal Dose
Administration
Contra Indications
Hypersensitivity to the drug
Precautions
Contact lenses should be removed prior to admin and can only be reinserted at least 15 min after drug admin as it contains benzalkonium chloride. Pregnancy.
Lactation: unknown whether distributed in breast milk, caution advised
Pregnancy-Lactation
Pregnancy Category: B
Lactation: unknown whether distributed in breast milk, caution advised
Interactions
Adverse Effects
Side effects of Lodoxamide :
>10%
Transient local burning (15%)
Transient local stinging (15%)
Transient local discomfort (15%)
1-10%
Headache (1.5%), Foreign body sensation (1-5%), Ocular itching/pruritus (1-5%), Blurred vision (1-5%), Dry eye (1-5%), Tearing/discharge (1-5%), Hyperemia (1-5%), Crystalline deposits (1-5%)
<1%
Heat sensation, Dizziness, Somnolence, Sneezing, Dry nose, Nausea, Stomach discomfort, Rash, Corneal erosion/ulcer, Scales on lid/lash, Eye pain, Ocular edema/swelling, Ocular warming sensation, Ocular fatigue, Chemosis, Corneal abrasion, Keratopathy, Keratitis, Blepharitis, Allergy, Sticky sensation, Epitheliopathy
Mechanism of Action
Lodoxamide has a mast cell stabilising effect. It is used as eye drops in the management of allergic conjunctivitis.