Lopinavir, Ritonavir

Indications

Lopinavir, Ritonavir is used for: LOPINAVIR
Indicated in combination with other antiretroviral agents for the treatment of hiv-infection
RITONAVIR
Indicated in combination with other antiretroviral agents for the treatment of hiv-infection

Adult Dose

Child Dose

Renal Dose

Administration

Contra Indications

Precautions

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Lopinavir, Ritonavir :

Mechanism of Action

LOPINAVIR
Lopinavir inhibits the hiv viral protease enzyme. This prevents cleavage of the gag-pol polyprotein and, therefore, improper viral assembly results. This subsequently results in non-infectious, immature viral particles
RITONAVIR
Ritonavir inhibits the hiv viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles