Naphazoline Nitrate 0.005% + Zinc Sulphate 0.02% Eye prep
Indications
Naphazoline Nitrate 0.005% + Zinc Sulphate 0.02% Eye prep is used for:
Conjunctival decongestant, Acute and chronic non-infectious conjunctivitis, Nonspecific conjunctival irritation, Bacterial and viral conjunctivitis, Irrigation of the tear ducts
Adult Dose
Ocular Vasoconstrictor/Decongestant
Temporary relief of ocular redness caused by irritation and relief of burning or irritation caused by dry eyes
Adults: 1-2 drops in the conjunctival sac, three to 4 times per day.
Child Dose
Ocular Vasoconstrictor/Decongestant
1 drop in the conjunctival sac, three to 4 times per day.
Renal Dose
Administration
Contra Indications
Hypersensitivity to zinc sulphate, Naphazoline and other ingredients. Nazin is contraindicated in patients suffering from narrow-angle glaucoma, dry eye and especially keratoconjunctivits sicca (Sjogren's syndrome). Nazin must not be used in infants.
Precautions
Patients with predisposition to glaucoma and in patients suffering from hypertension, cardiovascular diseases, pheochromocytoma, aneurysm, hyperglycemia, and hyperthyroidism.
Pregnancy-Lactation
Pregnancy Category: C
Lactation: not known if distributed in milk
Interactions
Adverse Effects
Side effects of Naphazoline Nitrate 0.005% + Zinc Sulphate 0.02% Eye prep :
Mydriasis and a slight increase of intraocular pressure in isolated cases. A slight and transient burning sensation may occur after instillation. Long term use may result in reactive redness of the eye (rebound effect).
In very rare cases systemic cardiovascular effects, such as hypertension and arrhythmia, may occur. Nonspecific fatigue has been observed in some patients.
Mechanism of Action
Naphazoline, an imidazoline derivative sympathomimetic amine, produces vasoconstriction by stimulating the alpha-adrenergic receptors in the arterioles of the conjunctiva and the nasal mucosa.
Zinc sulfate: Astringent.