Nedocromil sodium
Indications
Nedocromil sodium is used for:
Chronic asthma
Adult Dose
Inhalation
Chronic asthma
Adult: As sodium: 4 mg inhaled 4 times daily; reduce to bid once desired clinical response is observed.
Child Dose
Inhalation
Chronic asthma
Child: >6 yr: As sodium: 4 mg inhaled 4 times daily; reduce to bid once desired clinical response is observed.
Renal Dose
Administration
Contra Indications
Hypersensitivity.
Precautions
Pregnancy and lactation. Not for use in acute asthma attacks; acute bronchospasm. Children <6 yr; monitor closely.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Nedocromil sodium :
Inhalation: Unpleasant taste, headache, fatigue, nausea, vomiting, dyspepsia, diarrhoea, abdominal pain, conjunctivitis, cough, pharyngitis, rhinitis, upper respiratory infection.
Mechanism of Action
Nedocromil is a mast-cell stabiliser. It inhibits mediator release and bronchoconstriction induced by various stimuli and affects various inflammatory cells.