Nikethamide
Indications
Nikethamide is used for:
Energy malnutrition, Central respiratory depression, Tranquilizer overdoses
Adult Dose
Adult
1.500 g as Single Dose.
Child Dose
Renal Dose
Administration
Contra Indications
Nikethamide is contraindicated in conditions like Porphyria, Hypersensitivity to any component of product.
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Nikethamide :
The symptomatic adverse reactions produced by Nikethamide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Itching, Breathlessness, Paresthesias, Heat sensation.
Mechanism of Action
Nikethamide is a stimulant which mainly affects the respiratory cycle. Direct stimulation of respiratory center. Reflex stimulation of respiratory center by stimulating chemoceptor of carotid body.