Olopatadine 0.7% Eye prep

Indications

Olopatadine 0.7% Eye prep is used for: Allergic conjunctivitis

Adult Dose

Adults: One drop in each affected eye once a day.

Child Dose

Children (above 2 years of age): One drop in each affected eye once a day.

Renal Dose

Administration

Contra Indications

It is contraindicated incase of hypersensitivity to Olopatadine or to any component of the preparation.

Precautions

Not intended for contact lens-related irritation. Pregnancy and lactation. Remove contact lenses prior to eye admin. Reinsert contact lenses 10 min after admin. Do not wear contact lenses if eyes are red. Improper handling may contaminate soln w/ bacteria that may cause ocular infections. Tip of the dispensing container should not be in contact w/ eye, eyelids or surrounding structures. Monitoring Parameters. Lactation: Unknown if distributed into breast milk; use caution

Pregnancy-Lactation

Interactions

May result in additive CNS depression w/ CNS depressants.

Adverse Effects

Side effects of Olopatadine 0.7% Eye prep : 1-10% Headache (7%), Asthenia (<5%), Blurred vision (<5%), Burning or stinging (<5%), Cold syndrome (<5%), Dry eye (<5%), Foreign body sensation (<5%), Hyperemia (<5%), Hypersensitivity (<5%), Keratitis (<5%), Lid edema (<5%), Nausea (<5%), Pharyngitis (<5%), Pruritus (<5%), Rhinitis (<5%), Sinusitis (<5%), Taste perversion (<5%)

Mechanism of Action

Olopatadine is a relatively selective histamine H1-receptor antagonist which inhibits the release of histamine from mast cells and histamine-induced effects on conjunctival epithelial cells. It shares many of the pharmacologic effects of mast cell stabilisers.