Oxymetazoline Hydrochloride .05 % Nasal prep

Indications

Oxymetazoline Hydrochloride .05 % Nasal prep is used for: Sinusitis, Hay fever, Common cold, Acute or chronic rhinitis, Nasal congestion

Adult Dose

Nasal Nasal congestion Adult: Instil 2-3 drops or sprays in each nostril twice daily for 3-5 days.

Child Dose

Nasal Nasal congestion Child: <6 years: Safety and efficacy not established Child: >6 yr: Instil 2-3 drops or sprays in each nostril twice daily for 3-5 days.

Renal Dose

Administration

Contra Indications

Contraindicated in patients hypersensitive to Oxymetazoine Hydrochloride.

Precautions

Prolonged use may result in rebound congestion. Since oxymetazoline has systemic adverse effects, it should be used with caution in patients with hypertension, cardiovascular disease or hyperthyroidism or in those receiving MAO inhibitors.

Pregnancy-Lactation

Interactions

Potentially Fatal: Hypertensive crisis with MAOIs.

Adverse Effects

Side effects of Oxymetazoline Hydrochloride .05 % Nasal prep : Local stinging or burning, sneezing, dryness of mouth and throat. Prolonged or frequent use may cause rebound congestion. Headache, insomnia, tachycardia, hypertension, nervousness, nausea, dizziness, palpitation, arrhythmia.

Mechanism of Action

Oxymetazoline is a direct-acting sympathomimetic which has vasoconstrictor effect on mucosal blood vessels when applied topically and in turn reduces oedema of the nasal mucosa.