Pemirolast Potassium 0.1% Eye prep
Indications
Pemirolast Potassium 0.1% Eye prep is used for:
Allergic conjunctivitis
Adult Dose
Ophthalmic
Prophylaxis of allergic conjunctivitis
Adult: As 0.1% ophthalmic solution: Instill 1-2 drops into the affected eye(s) 4 times daily.
Child Dose
Ophthalmic
Prophylaxis of allergic conjunctivitis
Child: >3 yr: As 0.1% ophthalmic solution: Instill 1-2 drops into the affected eye(s) 4 times daily.
Renal Dose
Administration
Contra Indications
Contraindicated in patients with previously demonstrated hypersensitivity to any of the ingredients of this product.
Precautions
Not for treatment of contact lens-related irritation. Contact lens should be removed prior to drug admin and reinserted only at least 10 minutes after application. Safety and efficacy have not been established in children <3 yr. Pregnancy and lactation.
Lactation: Distributed in breast milk; caution advised
Pregnancy-Lactation
Pregnancy Category: C
Lactation: Distributed in breast milk; caution advised
Interactions
Adverse Effects
Side effects of Pemirolast Potassium 0.1% Eye prep :
1-10%
Burning, Dry eyes, Foreign body sensation, Ocular discomfort, Allergy, Bronchitis, Cough, Sneezing, Nasal congestion
Mechanism of Action
Pemirolast is a mast cell stabiliser that inhibits the in vivo Type I immediate hypersensitivity reaction. It inhibits chemotaxis of eosinophils into the ocular tissue and blocks the release of mediators. It is also reported to prevent calcium influx into mast cells following antigen stimulation. It has also been used in the treatment of chronic asthma and prophylaxis of allergic rhinitis.