Phenylephrine 0.12% + Tetryzoline Hydrochloride 0.04% + Zinc Sulphate 0.1% Eye prep

Indications

Phenylephrine 0.12% + Tetryzoline Hydrochloride 0.04% + Zinc Sulphate 0.1% Eye prep is used for: Dry eye, Burning, Red eye, Eye irritation, Discomfort of the eye

Adult Dose

Adult Eye Redness/Itching Instill 1 to 2 drops in the affected eye(s) up to 4 times daily.

Child Dose

Eye Redness/Itching Child >6 years: Instill 1 to 2 drops in the affected eye(s) up to 4 times daily.

Renal Dose

Administration

Contra Indications

Precautions

Sympathomimetics are generally contraindicated in patients with narrow-angle glaucoma. Contact lenses should be removed before use. Patients should be instructed to avoid allowing the tip of the container to contact the eye, eyelid, fingers or any other surface. Overuse may result in rebound congestion. Patients should be advised to discontinue use and notify their physician if their condition worsens or lasts for more than 72 hours.

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Phenylephrine 0.12% + Tetryzoline Hydrochloride 0.04% + Zinc Sulphate 0.1% Eye prep : Blurred vision; minor stinging or tingling when the medicine is dropped into the eye. Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; eye pain; worsening or persistent eye irritation or redness.

Mechanism of Action

Tetryzoline is a sympathomimetic with alpha-adrenergic activity with little or no effect on beta-adrenergic receptors. Phenylephrine is a sympathomimetic with mainly direct effects on alpha-adrenergic receptors and weak beta-adrenergic activity. It causes vasoconstriction of the arterioles of the nasal mucosa and conjunctiva; activates the dilator muscle of the pupil to cause contraction; produces vasoconstriction of arterioles in the body and produces systemic arterial vasoconstriction. Zinc: Cofactor in over 100 enzymes; plays a role in DNA synthesis; supports a healthy immune system; helps maintain a sense of smell and taste; may assist in porper function of insulin.