Pivampicillin, Pivmecillinam

Indications

Pivampicillin, Pivmecillinam is used for: PIVAMPICILLIN
Or the treatment of respiratory tract infections (including acute bronchitis, acute exacerbations of chronic bronchitis and pneumonia); ear, nose and throat infections; gynecological infections; urinary tract infections (including acute uncomplicated gonococcal urethritis) when caused by non penicillinase-producing susceptible strains of the following organisms: gram-positive organisms, e. G. , streptococci, pneumococci and staphylococci; gram-negative organisms, e. G. , h. Influenzae, n. Gonorrhoeae, e. Coli, p. Mirabilis
PIVMECILLINAM
Used to treat infections due to mecillinam-sensitive organisms such as urinary tract infections, salmonellosis and typhoid fever

Adult Dose

Child Dose

Renal Dose

Administration

Contra Indications

Precautions

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Pivampicillin, Pivmecillinam :

Mechanism of Action

PIVAMPICILLIN
Ampicillin (the active metabolite of pivampicillin) has a bactericidal action resulting from inhibition of cell wall mucopeptide biosynthesis
PIVMECILLINAM
Pivmecillinam interferes with the biosynthesis of the bacterial cell wall however its activity is slightly different from that of other penicillins and cephalosporins