Precipitated Sulpher 10% + Salicylic Acid 3%
Indications
Precipitated Sulpher 10% + Salicylic Acid 3% is used for:
Acne, Seborrheic dermatitis, Scalp disorders, Hyperkeratotic, Scaling skin conditions, Calluses, Dandruff
Adult Dose
Topical/Cutaneous
Using as a soap, wetting skin and washing face and other affected areas; rinsing thoroughly; patting dry
Acne
Adult: Apply thinly to affected area 1-3 times daily, reduce to once daily or every other day if dryness or peeling occur.
Hyperkeratotic and scaling skin conditions
Adult: Apply to affected area of the skin and/or scalp 1-4 times daily.
Child Dose
Renal Dose
Administration
Contra Indications
Hyppersensitivity.
Precautions
Avoiding simultaneous use with other topical acne preparations or preparations containing peeling agents, alcohol-containing preparations, abrasive soaps or cleansers, cosmetics or soaps with drying effect, medicated cosmetics, or other topical skin medication, unless otherwise directed by physician.
Avoiding concurrent use with topical mercury-containing preparations
Caution if medications containing aspirin or other salicylates are used
Pregnancy-Lactation
Interactions
Increased risk of skin dryness and irritation w/ other topical acne preparations.
Adverse Effects
Side effects of Precipitated Sulpher 10% + Salicylic Acid 3% :
Dermatitis, skin peeling, discomfort, irritation, dryness, ulceration or erosion; systemic effects including salicylate toxicity (e.g. nausea, vomiting, dizziness, lethargy, hyperpnoea, diarrhoea, and psychosis), and toxic inner ear damage.
Potentially Fatal: Rarely, serious hypersensitivity reactions (e.g. anaphylactic reaction).
Mechanism of Action
Salicylic acid is a potent keratolytic with mild antiseptic action when applied topically. Sulfur topical is a scabicide and keratolytic agent.
The mechanism of action when these two ingredients are combined, may be a synergistic keratolytic effect. The mechanism of action of salicylic acid in the treatment of acne may also include anti-inflammatory activity.