Prednisolone 1% Eye prep

Indications

Prednisolone 1% Eye prep is used for: Conjunctivitis, steroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe.

Adult Dose

Ophthalmic Conjunctivitis Adult: Instill 1-2 drops into the affected eye(s) 2-4 times daily. Higher frequency may be used during the initial 24-48 hr, if needed.

Child Dose

Renal Dose

Administration

Contra Indications

Epithelial defect, glaucoma, herpes, vaccinia, varicella, and other viral diseases of cornea or conjunctiva, mycobacterial infection of eye, fungal diseases of ocular structures, hypersensitivity to any ingredients

Precautions

Prolonged use of corticosteroids may result in damage to the optic nerve and defects in vision. If this product is used for longer period of time, intraocular pressure should be routinely monitored.

Pregnancy-Lactation

Pregnancy Category: C Lactation: not known if distributed in milk

Interactions

Adverse Effects

Side effects of Prednisolone 1% Eye prep : Raised IOP and reduced visual function with possible development of glaucoma and infrequent optic nerve damage, posterior subcapsular cataract formation and delayed wound healing. Fungal and viral infections of the cornea are particularly may develop coincidentally with long-term applications of steroid.

Mechanism of Action

Prednisolone decreases inflammation by inhibition of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It suppresses the immune system by reducing the activity and production of the lymphocytes and eosinophils.