Salicylic Acid 10% + Urea 10% Topical
Indications
Salicylic Acid 10% + Urea 10% Topical is used for:
Psoriasis, Eczema, Warts, Keratosis, Xerosis, Corns, Callous
Adult Dose
Adult
Foot Care
Apply to affected area on feet once or twice daily.
Maximum benefit seen in 7 days.
Child Dose
Renal Dose
Administration
Contra Indications
It should not be used in any patient known to be sensitive to Salicylic Acid or any other listed ingredients.
Precautions
For external use only. Avoid contact with eyes and other mucous membranes.
Pregnancy-Lactation
Interactions
Urea...Increased excretion of lithium.
Adverse Effects
Side effects of Salicylic Acid 10% + Urea 10% Topical :
Mild, temporary burning, itching, irritation, or stinging.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); excessive burning, irritation, itching, peeling, redness, stinging, or tenderness of your skin.
Mechanism of Action
Salicylic acid has a potent keratolytic action and a slight antiseptic action when applied topically. It softens and destroys the stratum corneum by increasing endogenous hydration which causes the horny layer of the skin to swell, soften, and then desquamate. At high concentrations, salicylic acid has a caustic effect. It also possesses weak antifungal and antibacterial activity.
Applied topically, urea promotes hydration of keratin and mild keratolysis in dry skin. It increases water uptake by the stratum corneum and has an antipruritic effect.