Selenium Sulfide topical
Indications
Selenium Sulfide topical is used for:
Seborrhoeic dermatitis, Dandruff
Adult Dose
Topical/Cutaneous
Seborrhoeic dermatitis; Dandruff
Adult: As 2.5% shampoo or lotion: Massage into wet scalp, leave for 2-3 min then rinse thoroughly. Use twice wkly for 2 wk, may repeat at less frequent intervals subsequently.
As 1% shampoo or lotion: Appy 1-2 times wkly.
Topical/Cutaneous
Tinea versicolor
Adult: As 2.5% lotion: Apply to affected areas, lather w/ a small amount of water and leave on skin for 10 min, then rinse thoroughly. Repeat procedure once daily for 7 days.
Child Dose
Topical/Cutaneous
Seborrhoeic dermatitis; Dandruff
Child: 5-14 yr As 2.5% shampoo or lotion: Massage into wet scalp, leave for 2-3 min then rinse thoroughly. Use twice wkly for 2 wk, may repeat at less frequent intervals subsequently.
As 1% shampoo or lotion: Appy 1-2 times wkly.
Renal Dose
Administration
Contra Indications
Hypersensitivity. Broken or severely inflamed skin.
Precautions
Avoid contact with all mucous membranes, including eyes, lips, broken/inflamed skin. Risk of systemic toxicity. Discontinue of redness or irritation occur. Patient Counselling Remove gold, silver and other metallic jewellery prior to use. Avoid use of shampoo w/in 48 hr of applying hair dye, straightening or waving preparations.
Pregnancy-Lactation
Pregnancy Category: C
Lactation: not known if distributed in human milk; use cation
Interactions
Adverse Effects
Side effects of Selenium Sulfide topical :
Skin irritation, esp in the genital areas and skin folds; oily scalp, hair discouloration, hair loss.
Mechanism of Action
Selenium sulfide has antifungal and antiseborrhoeic properties. It is active against Pityrosporum ovale, a yeast-like fungus that is part of the normal flora of the scalp. It also has a cytostatic effect on cells of the epidermis and follicular epithelium, thus reducing corneocyte production.