Sodium Chloride oral prep

Indications

Sodium Chloride oral prep is used for: Treatment and prophylaxis of Sodium Chloride deficiency.

Adult Dose

Adults Tablet For prophylaxis 8-16 tablets per day. For treatment dosage to be adjusted to individual needs up to a maximum of 40 tablets per day in case of severe salt depletion. For control of muscle cramps during routine maintenance haemodialysis usually 20-32 tablets per dialysis. In some cases of chronic renal salt-wasting, up to 40 tablets per day may be required with appropriate fluid intake.

Child Dose

Renal Dose

Dosage adjustment may be necessary.

Administration

Tablet should be swallowed whole with water (approx. 70 ml per tablet where kidney function is normal to avoid hypernatremia), and not chewed.

Contra Indications

Sodium Chloride is contra-indicated in any situation where salt retention is undesirable, such as edema, heart disease, cardiac decompensation and primary or secondary aldosteronism; or where therapy is being given to produce salt and water loss.

Precautions

Hypertension, heart failure, peripheral or pulmonary oedema, impaired renal function, liver cirrhosis, preeclampsia. Preganancy & Lactation. Maintain adequate water intake.

Pregnancy-Lactation

US FDA Pregnancy category C

Interactions

May affect serum concentrations of lithium.

Adverse Effects

Side effects of Sodium Chloride oral prep : Hypernatraemia; thirst, reduced salivation and lachrymation, fever, tachycardia, hypertension, headache, dizziness, restlessness, irritability and weakness.

Mechanism of Action