Sodium picosulphate
Indications
Sodium picosulphate is used for:
used as a treatment for constipation or to prepare the large bowel before colonoscopy or surgery
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Sodium picosulphate :
Mechanism of Action
Sodium picosulfate is a prodrug. It has no significant direct physiological effect on the intestine, however it is metabolised by gut bacteria into the active compound 4,4'-dihydroxydiphenyl-(2-pyridiyl)-methane (DPM, BPHM). This compound is a stimulant laxative and increases peristalsis in the gut.