Sodium sulfacetamide + Sulfur topical

Indications

Sodium sulfacetamide + Sulfur topical is used for: Acne, Seborrheic Dermatitis

Adult Dose

Acne Indicated in the topical control of acne vulgaris and rosacea Cream: Cleanse thoroughly with soap and water before applying thin layer to affected areas qDay/TID PRN Foam: Cleanse thoroughly before massaging foam into affected area qDay-BID; if removing, rinse off after 1-2 minutes Cleanser: Apply to wet skin and massage gently qDay/BID; rinse thoroughly and pat dry Cleansing Pads: Apply wet pad to wet skin and work into full lather for 10-20 seconds, avoiding eyes; rinse thoroughly and pat dry; discard used To minimize potential dryness, start with 1 application daily, then gradually increase to 2-3 times daily as needed Seborrheic Dermatitis Indicated in the topical control of acne vulgaris and rosacea Cream: Cleanse thoroughly with soap and water before applying thin layer to affected areas qDay/TID PRN Foam: Cleanse thoroughly before massaging foam into affected area qDay-BID; if removing, rinse off after 1-2 minutes Cleanser: Apply to wet skin and massage gently qDay/BID; rinse thoroughly and pat dry Cleansing Pads: Apply wet pad to wet skin and work into full lather for 10-20 seconds, avoiding eyes; rinse thoroughly and pat dry; discard used To minimize potential dryness, start with 1 application daily, then gradually increase to 2-3 times daily as needed

Child Dose

Acne Vulgaris Adolescents Cream: Cleanse thoroughly with soap and water before applying thin layer to affected areas qDay/TID PRN Foam: Cleanse thoroughly before massaging foam into affected area qDay-BID; if removing, rinse off after 1-2 minutes Cleanser: Apply to wet skin and massage gently qDay/BID; rinse thoroughly and pat dry Cleansing Pads: Apply wet pad to wet skin and work into full lather for 10-20 seconds, avoiding eyes; rinse thoroughly and pat dry; discard used To minimize potential dryness, start with 1 application daily, then gradually increase to 2-3 times daily as needed

Renal Dose

Administration

Contra Indications

Hypersensitivity to sulfa drugs

Precautions

External use only Avoid contact with eyes or mucous membranes Avoid UV exposure Discontinue if excessive skin irritation develops Severe reactions including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia, and other blood dyscrasias reported

Pregnancy-Lactation

Pregnancy Category: C Lactation: Unknown whether excreted in breast milk, use caution

Interactions

Adverse Effects

Side effects of Sodium sulfacetamide + Sulfur topical : Frequency Not Defined Local irritation Pruritus Erythema Itching Edema

Mechanism of Action

Sulfacetamide: Para-aminobenzoic acid (PABA) inhibitor; restricts folic acid synthesis required for bacterial growth Sulfur: Elicits antiseptic, antiparasitic, antiseborrheic, and keratolytic actions