Tioconazole Vag prep
Indications
Tioconazole Vag prep is used for:
Vulbo-Vaginal candidiasis
Adult Dose
Vaginal
Vaginal candidiasis
Adult: As vaginal Ointment: One full applicator of Vaginal Ointment administered intravaginally at bedtime as a single dose.
As vaginal suppository: 300 mg as a single dose P/V.
Child Dose
Vaginal
Vaginal candidiasis
Child> 12 years: As vaginal Ointment: One full applicator of Vaginal Ointment administered intravaginally at bedtime as a single dose.
As vaginal suppository: 300 mg as a single dose P/V.
Renal Dose
Administration
Contra Indications
Hypersensitivity to imidazole-derivative azole antifungal. Self-medication in women with diabetes or HIV infection. Girls <12 yr.
Precautions
Self-medication in patient w/ DM, HIV infection. Girls <12 yr (vag). Pregnancy and lactation. Patient Counselling Vag: Avoid sexual intercourse. Condoms and diaphragms may be damaged and fail to prevent pregnancy or STD, may resume usage 3 days after treatment. Avoid using tampons, douches, spermicides or other vag products.
Lactation: not known whether distributed into milk, manufacturer recommends women discontinue breastfeeding while receiving drug
Pregnancy-Lactation
Pregnancy Category: C
Lactation: not known whether distributed into milk, manufacturer recommends women discontinue breastfeeding while receiving drug
Interactions
Adverse Effects
Side effects of Tioconazole Vag prep :
1-10%
Vulvovaginal burning, vaginitis, pruritus (5-6%), Headache (5%), Infection (3%), Abdominal pain (2%), Dysuria, nocturia, pharyngitis, and rhinitis (<2%)
Mechanism of Action
Tioconazole, a synthetic azole antifungal, interferes w/ synthesis of ergosterol which is needed for fungal cell membrane synthesis.