Triamcinolone Acetonide 0.1% Topical
Indications
Triamcinolone Acetonide 0.1% Topical is used for:
Inflammatory skin conditions
Adult Dose
Topical/Cutaneous
Inflammatory skin conditions
Adult: Apply cream/ointment sparingly onto affected area 2-3 times daily.
Child Dose
Topical/Cutaneous
Inflammatory skin conditions
Adult: Apply cream/ointment sparingly onto affected area 2-3 times daily.
Renal Dose
Administration
Contra Indications
Untreated systemic fungal, bacterial, viral or parasitic infection, hypersensitivity.
Precautions
Diabetes; hypertension, renal and liver impairment; glaucoma; psychosis; delayed tissue healing; cirrhosis; heart failure; recent MI; hypothyroidism; osteoporosis; peptic ulceration; thromboembolic disorders. Monitor height in children on prolonged therapy. Avoid rapid drug withdrawal. Elderly, children, pregnancy, lactation.
Pregnancy-Lactation
Pregnancy category: C
Lactation: Not known whether topical corticosteroids are distributed into milk; however, systemic corticosteroids are distributed into milk; use with caution
Interactions
Lowering of plasma salicylates levels. Increased risk of GI bleeding and ulceration with NSAIDs. Antagonised blood glucose-lowering effects of the antidiabetics. Increased risk of hyperkalaemia with amphotericin B, beta agonists, beta-blockers, potassium-depleting diuretics, theophylline. Increased clearance of the triamcinolone with ciclosporin, carbamazepine, phenytoin, barbiturate, rifampicin. Infections may develop if given with live vaccines.
Adverse Effects
Side effects of Triamcinolone Acetonide 0.1% Topical :
Skin atrophy, Striae, Acneform lesions, Pigmentation changes, HPA suppression (with higher potency used >2 weeks)Systemic absorption if applied to large areas, broken skin or under occlusive dressing.
Mechanism of Action
Triamcinolone has mainly glucocorticoid activity. It suppresses the migration of polymorphonuclear leukocytes and reduces capillary permeability thereby decreasing inflammation.