Triamcinolone Acetonide Mouth prep
Indications
Triamcinolone Acetonide Mouth prep is used for:
Mouth ulceration
Adult Dose
Mouth/Throat
Mouth ulceration
Adult: A small amount (about 0.6 cm) of the 0.1% paste is pressed onto the lesion without rubbing until a thin film develops.
Apply 2 or 3 times daily, preferably after meals.
Re-evaluate if recovery does not occur after 7 days of treatment.
Child Dose
Renal Dose
Administration
Contra Indications
Untreated systemic fungal, bacterial, viral or parasitic infection, hypersensitivity.
Precautions
Diabetes; hypertension, renal and liver impairment; glaucoma; psychosis; delayed tissue healing; cirrhosis; heart failure; recent MI; hypothyroidism; osteoporosis; peptic ulceration; thromboembolic disorders. Monitor height in children on prolonged therapy. Avoid rapid drug withdrawal. Elderly, children, pregnancy, lactation.
Pregnancy-Lactation
Interactions
Lowering of plasma salicylates levels. Increased risk of GI bleeding and ulceration with NSAIDs. Antagonised blood glucose-lowering effects of the antidiabetics. Increased risk of hyperkalaemia with amphotericin B, beta agonists, beta-blockers, potassium-depleting diuretics, theophylline. Increased clearance of the triamcinolone with ciclosporin, carbamazepine, phenytoin, barbiturate, rifampicin. Infections may develop if given with live vaccines.
Adverse Effects
Side effects of Triamcinolone Acetonide Mouth prep :
Local burning, itching, irritation, GI upsets; increased fragility of mucosa of the mouth.
Mechanism of Action
Triamcinolone has mainly glucocorticoid activity. It suppresses the migration of polymorphonuclear leukocytes and reduces capillary permeability thereby decreasing inflammation.