Tulobuterol Hydrochloride
Indications
Tulobuterol Hydrochloride is used for:
Chronic obstructive pulmonary disease
Adult Dose
Oral
Bronchodilation
Adult: Initially, 1-2 mg bid, increase to 2 mg tid if necessary.
Child Dose
Oral
Bronchodilation
Child: 1-6 yr: 0.25-0.5 mg bid,
6-10 yr: 0.5-1 mg bid,
10-14 yr: 1-1.5 mg bid.
Renal Dose
Administration
Contra Indications
Phaeochromocytoma.
Precautions
Hyperthyroidism, myocardial insufficiency, arrhythmias, susceptibility to QT-interval prolongation, hypertension and DM.
Pregnancy-Lactation
Interactions
Increased risk of arrhythmia with digoxin. Hypokalaemia with concomitant admin of xanthines, corticosteroids and diuretics.
Adverse Effects
Side effects of Tulobuterol Hydrochloride :
Fine tremor of skeletal muscle, palpitations, muscle cramps, tachycardia, nervous tension, headache, peripheral vasodilatation, hypersensitivity reactions.
Mechanism of Action
Tulobuterol is a direct-acting sympathomimetic with selective action on ?2-receptors. It is available orally, as a inhaler and as a transdermal patch. It is given as the hydrochloride by mouth and the base as transdermal formulation and inhalation.