Vitamin A + D + C + Vitamin B-complex Paediatric prep

Indications

Vitamin A + D + C + Vitamin B-complex Paediatric prep is used for: For prevention and treatment of vitamin deficiency in children and infants.

Adult Dose

Child Dose

Oral As Paediatric drop Child <1 year : 9-10 drops (0.3 ml), 1 year and above : 23-25 drops (1.0 ml) once daily.

Renal Dose

Administration

Contra Indications

Supplemental vitamins should not be prescribed for patients with haemochromatosis or Wilson’s disease. Hypersensitivity to any of the ingredients is contraindicated. Excessive doses of vitamin A and D can lead to hypervitaminosis. When multivitamin preparations are prescribed allowance must be made for vitamins from other sources.

Precautions

Pregnancy-Lactation

Interactions

Vitamin a.....Decreased absorption with neomycin. Increased risk of hypervitaminosis A with synthetic retinoids eg, acitretin, isotretinoin and tretinoin. Increased risk of toxicity when used with alcohol.

Adverse Effects

Side effects of Vitamin A + D + C + Vitamin B-complex Paediatric prep : Multivitamin preparation with ordinary doses of component are usually nontoxic.

Mechanism of Action

Vitamin A plays an essential role in the function of retina and is essential for growh and differentiation of epithelial tissue. Vitamin B: Plays a role in the synthesis and maintenance of coenzyme A. Necessary for lipid metabolism, carbohydrate metabolism, tissue respiration, glycogenolysis, inhibition of very low-density lipoprotein (VLDL) synthesis. May increaase chylomicron triglyceride removal from plasma. Vitamin B12 (cyanocobalamin): Required for the maintenance of normal erthropoiesis, nucleprotein and myelin synthesis, cell reproduction and normal growth; intrinsic factor, a glycoprotein secreted by the gastric mucosa, is required for active absorption of Vitamin B12 from the GI tract. Necessary for normal tissue respiration; plays a role in activation of pyridoxine and conversion of tryptophan to niacin. Vitamin C: Necessary for collagen formation and tissue repair; plays a role in oxidation/reduction reactions as well as other metabolic pathways including synthesis of catecholamines, carnitine, and steroids; also plays a role in conversion of folic acid to folinic acid. Vitamin D is supplemented for prevention and cure of nutritional and metabolic rickets and for treatment of hypoparathyroidism.