Vitamin B complex
Indications
Vitamin B complex is used for:
Vitamin B deficiency. Glossitis, stomatitis, cheilosis, beriberi polyneuritis.
Adult Dose
Oral
Adult:
Tablet/Capsule : 1-2 tab/cap, 3 times daily.
Syrup : 1-2 (5 ml spoonful) syrup three times a day.
Child Dose
Oral
Children: 1 (5 ml spoonful) syrup three times a day.
Infants: 1 (5 ml spoonful) syrup daily.
Renal Dose
Administration
Contra Indications
Contraindicated in patients hypersensitive to any of its components.
Precautions
Should be given cautiously to patients taking Levodopa as Pyridoxine reduces the effect of Levodopa.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Vitamin B complex :
Generally well tolerated.
Mechanism of Action
Vitamin B: Plays a role in the synthesis and maintenance of coenzyme A. Necessary for lipid metabolism, carbohydrate metabolism, tissue respiration, glycogenolysis, inhibition of very low-density lipoprotein (VLDL) synthesis. May increase chylomicron triglyceride removal from plasma.
Vitamin B12 (cyanocobalamin): Required for the maintenance of normal erythropoiesis, nucleoprotein and myelin synthesis, cell reproduction and normal growth; intrinsic factor, a glycoprotein secreted by the gastric mucosa, is required for active absorption of Vitamin B12 from the GI tract. Necessary for normal tissue respiration; plays a role in activation of pyridoxine and conversion of tryptophan to niacin.