Brevibloc Injection

Esmolol
10mg/ml
DUPONT PHARMACEUTICALS
Pack size 10ml Vial x 20
Dispensing mode POM
Source USA
AgentCITY MEDICAL STORE
Retail Price 259.50 AED

Available as:

Indications

Brevibloc Injection is used for: For the rapid control of ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other emergent circumstances where short term control of ventricular rate with a short-acting agent is desirable. Also used in noncompensatory sinus tachycardia where the rapid heart rate requires specific intervention

Adult Dose

Child Dose

Renal Dose

Administration

Contra Indications

Precautions

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Esmolol :

Mechanism of Action

Similar to other beta-blockers, esmolol blocks the agonistic effect of the sympathetic neurotransmitters by competing for receptor binding sites. Because it predominantly blocks the beta-1 receptors in cardiac tissue, it is said to be cardioselective. In general, so-called cardioselective beta-blockers are relatively cardioselective; at lower doses they block beta-1 receptors only but begin to block beta-2 receptors as the dose increases. At therapeutic dosages, esmolol does not have intrinsic sympathomimetic activity (isa) or membrane-stabilizing (quinidine-like) activity. Antiarrhythmic activity is due to blockade of adrenergic stimulation of cardiac pacemaker potentials. In the vaughan williams classification of antiarrhythmics, beta-blockers are considered to be class ii agents

Note

Brevibloc 10mg/ml Injection manufactured by DUPONT PHARMACEUTICALS. Its generic name is Esmolol. Brevibloc is availble in United Arab Emirates. Farmaco UAE drug index information on Brevibloc Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Esmolol :