Brevibloc Injection
Esmolol
250mg/ml
DUPONT PHARMACEUTICALS
| Pack size | 10ml Ampoule x 10 |
|---|---|
| Dispensing mode | POM |
| Source | USA |
| Agent | CITY MEDICAL STORE |
| Retail Price | 765.50 AED |
Available as:
Indications
Brevibloc Injection is used for:
For the rapid control of ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other emergent circumstances where short term control of ventricular rate with a short-acting agent is desirable. Also used in noncompensatory sinus tachycardia where the rapid heart rate requires specific intervention
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Esmolol :
Mechanism of Action
Similar to other beta-blockers, esmolol blocks the agonistic effect of the sympathetic neurotransmitters by competing for receptor binding sites. Because it predominantly blocks the beta-1 receptors in cardiac tissue, it is said to be cardioselective. In general, so-called cardioselective beta-blockers are relatively cardioselective; at lower doses they block beta-1 receptors only but begin to block beta-2 receptors as the dose increases. At therapeutic dosages, esmolol does not have intrinsic sympathomimetic activity (isa) or membrane-stabilizing (quinidine-like) activity. Antiarrhythmic activity is due to blockade of adrenergic stimulation of cardiac pacemaker potentials. In the vaughan williams classification of antiarrhythmics, beta-blockers are considered to be class ii agents
Note
Brevibloc 250mg/ml Injection manufactured by DUPONT PHARMACEUTICALS. Its generic name is Esmolol. Brevibloc is availble in United Arab Emirates.
Farmaco UAE drug index information on Brevibloc Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.