Scopinal Syrup

Hyoscine Butyl Bromide
1mg/ml
Julphar (Gulf Pharmaceutical Industries)
Pack size 100ml Bottle
Dispensing mode POM
Source UAE
AgentJULPHAR
Retail Price 21.00 AED

Available as:

20mg/ml - Injection 10mg - Tablets / Film-coated 20mg/ml - Injection 10mg - Tablets / Film-coated 10mg - Tablets / Film-coated

Indications

Scopinal Syrup is used for: Gastrointestinal tract spasm, Abdominal pain, Genitourinary spasm

Adult Dose

Oral Gastrointestinal tract spasm; Genitourinary spasm Adult: 20 mg 4 times daily. Parenteral Gastrointestinal tract spasm; Genitourinary spasm Adult: 20 mg IM/IV repeated after 30 min if needed. Max Dosage: 100 mg daily.

Child Dose

Oral Gastrointestinal tract spasm; Genitourinary spasm Child: 6-12 yr: 10 mg tid.

Renal Dose

Administration

Contra Indications

Narrow-angle glaucoma, acute haemorrhage, paralytic ileus, tachycardia due to cardiac insufficiency, myasthenia gravis.

Precautions

Hepatic/renal disease, pyloric stenosis, urinary retention, prostatic hyperplasia, psychosis, seizure disorders, ulcerative colitis, coronary artery disease, tachyarrhythmias, heart failure, hypertension. Elderly, children, pregnancy, lactation.

Pregnancy-Lactation

Interactions

Additive sedative effects with alcohol or other CNS depressants. Reduced effects with acetylcholinesterase inhibitors (donepezil, galantamine, rivastigmine, tacrine). Potentially Fatal: Effect potentiated by other anticholinergic drugs and TCAs.

Adverse Effects

Side effects of Hyoscine Butyl Bromide : Flushing, postural hypotension, tachycardia, fibrillation. Rarely psychotic reactions. Dizziness, drowsiness, fatigue, headache, memory loss. Dry skin, erythema, increased sensitivity to light, rash. Bloatedness, constipation, dry throat, dysphagia, nausea, vomiting, xerostomia. Dysuria, urinary retention. Tremor, weakness. Impaired accommodation, blurred vision, cycloplegia, dryness, narrow-angle glaucoma, increased intraocular pain, itching, photophobia, pupil dilation. Dry nose. Decreased diaphoresis, heat intolerance. Ophthalmic: Somnolence, dermatitis, oedema, exudate, follicular conjunctivitis, increased IOP, local irritation, photophobia, vascular and respiratory congestion. Potentially Fatal: CNS depression, coma, circulatory and respiratory failure.

Mechanism of Action

Hyoscine competitively blocks muscarinic receptors and has central and peripheral actions. It relaxes smooth muscle and reduces gastric and intestinal motility.

Note

Scopinal 1mg/ml Syrup manufactured by Julphar (Gulf Pharmaceutical Industries). Its generic name is Hyoscine Butyl Bromide. Scopinal is availble in United Arab Emirates. Farmaco UAE drug index information on Scopinal Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Hyoscine Butyl Bromide :

Syrup
Spasmopan 1mg/ml
The Arab Parm. Mfg. Co (APM)
Injection
Spasmopan 20mg/ml
The Arab Parm. Mfg. Co (APM)
Tablets / Coated
Spasmonore 10mg
The Jordanian Pharmaceutical Manufacturing Company
Syrup
Spasmolife 5mg/5ml
Lifepharma FZE
Rectal Suppositories
Spasmanore 10mg
The Jordanian Pharmaceutical Manufacturing Company