Tenol Tablets / Film-coated
Atenolol
50mg
Kuwait Saudi Pharmaceutical Industries Co. (KSPICO)
| Pack size | 20's (10's Blister x 2) |
|---|---|
| Dispensing mode | POM |
| Source | KUWAIT |
| Agent | INSPIRE DRUG STORE |
| Retail Price | 21.00 AED |
Available as:
Indications
Tenol Tablets / Film-coated is used for:
Hypertension, Migraine, Arrhythmias, MI, Angina pectoris
Adult Dose
Adult
Hypertension
25-50 mg/day PO initially; may be increased to 100 mg/day PO
Angina Pectoris
50 mg/day PO; after 1 week, may be increased to 100 mg/day PO; some patients may require 200 mg/day
Post Myocardial Infarction
Secondary prevention
100 mg PO once daily or divided q12hr for 6-9 days after myocardial infarction (MI)
Elderly
May be necessary to initiate dosing at 25 mg/day PO
Hypertension
25 mg/day PO initially; may be increased to 100 mg/day PO
Angina Pectoris
25 mg/day PO; after 1 week, may be increased to 100 mg/day; some patients may require 200 mg/day
Post Myocardial Infarction
Secondary prevention
100 mg PO once daily or divided q12hr for 6-9 days after MI
Child Dose
Renal Dose
Renal impairment:
CrCl (ml/min)
<15 25 mg or 50 mg on alternate days.
15-35 50 mg/day.
Dialysis patients 25-50 mg after each dialysis.
Administration
May be taken with or without food.
Contra Indications
Hypersensitivity. Sinus bradycardia, sinus node dysfunction, heart block >1st degree, compensated cardiac failure, cardiogenic shock, bronchospastic diseases, peripheral vascular diseases. Pregnancy.
Precautions
Compensated heart failure. Variant angina, acute MI, DM; peripheral vascular disorders; hepatic and renal dysfunction; elderly patients, children. Lactation. If atenolol and clonidine are co-admin, then gradual withdrawal of clonidine should take place a few days after withdrawal of atenolol.
Lactation: Drug enters breast milk; neonates born to mothers who are receiving atenolol at parturition or breastfeeding may be at risk for hypoglycemia and bradycardia; use with caution
Pregnancy-Lactation
Pregnancy category: D
Lactation: Drug enters breast milk; neonates born to mothers who are receiving atenolol at parturition or breastfeeding may be at risk for hypoglycemia and bradycardia; use with caution
Interactions
Concomitant admin w/ reserpine may increase hypotension and bradycardia. Additive w/ Ca channel blockers, hydralazine, methyldopa. Increased risk of bradycardia and heart block w/ verapamil and diltiazem. May decrease hypotensive effects w/ NSAIDs (e.g. indometacin). Enhanced bradycardic effect w/ disopyramide, amiodarone or digitalis glycosides. May exacerbate rebound HTN upon discontinuance of clonidine treatment.
Adverse Effects
Side effects of Atenolol :
>10%
Tiredness (13%)
1-10%
Hypotension (10%), Bradycardia (8%), Cold extremities (0.5- 7%), Postural hypotension (2-4%), Depression (3%), Nausea (2-3%), Dreaming (2%), Drowsiness (2%), Diarrhea (1-2%), Fatigue (1-2%), Leg pain (1-2%), Lethargy (1-2%), Lightheadedness (1-2%), Vertigo (1-2%), Dyspnea (0.4-2%), 2°/3° atrioventricular (AV) block (1%)
Frequency Not Defined
Hypotension, severe congestive heart failure (CHF), sick sinus syndrome, Catatonia, disorientation, emotional lability, hallucinations, headache, impaired performance on neuropsychometric tests, psychoses, short-term memory impairment, Purpura, rashes, Nausea, Thrombocytopenia, Elevated serum hepatic enzymes and bilirubin, Impotence, Peyronie disease, Antinuclear antibodies (ANA), lupus syndrome, Visual disturbances, xerophthalmia, Raynaud phenomenon
Potentially Fatal: Heart failure, 2nd or 3rd degree AV block.
Mechanism of Action
Atenolol is a competitive cardioselective beta1-blocker and does not have effect on ?beta2-receptors except in high doses. It reduces resting and exercise-induced heart rate as well as myocardial contractility.
Note
Tenol 50mg Tablets / Film-coated manufactured by Kuwait Saudi Pharmaceutical Industries Co. (KSPICO). Its generic name is Atenolol. Tenol is availble in United Arab Emirates.
Farmaco UAE drug index information on Tenol Tablets / Film-coated is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.
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