Vizol S 0.4% Drops ophthalmic
Sodium Hyaluronate
0.004
JADRAN - GALENSKI LABORATORIJ D.D,
| Pack size | 10ml HDPE Dropper Bottle |
|---|---|
| Dispensing mode | POM |
| Source | CROATIA |
| Agent | PHARMALINK |
| Retail Price | 54.00 AED |
Available as:
Indications
Vizol S 0.4% Drops ophthalmic is used for:
Osteoarthritis
Adult Dose
Intra-articular
Adult:
Osteoarthritis of Knee
Indicated for treatment of pain in osteoarthritis of the knee
Inject 20 mg (2 mL) once wkly for 3-5 weeks.
Child Dose
Safety & efficacy not established
Renal Dose
Administration
Contra Indications
Hypersensitivity to sodium hyaluronate or avian proteins. Intra-articular injections are contraindicated in cases of past and present infections or skin diseases in the area of the injection site.
Precautions
Use caution when injecting Sodium Hyaluronate into patients who are allergic to avian proteins, feathers, and egg products. Strict aseptic administration technique must be followed. Remove joint effusion, if present, before injecting Sodium Hyaluronate. Do not use the same syringe for removing joint effusion and for injecting Sodium Hyaluronate. It is recommended that the patient avoid any strenuous activities or prolonged (i.e., more than 1 hour) weight-bearing activities such as jogging or tennis within 48 hours following the intra-articular injection.
Lactation: Unknown whether distributed in breast milk, caution advised
Pregnancy-Lactation
Pregnancy Category: N/A
Lactation: Not known if excreted in breast milk; not recommended
Interactions
The safety and effectiveness of the use of sodium hyaluronate concomitantly with other intra-articular injection has not yet been established.
As sodium hyaluronate is precipitated by quaternary amine bactericides or disinfectants eg, benzalkonium chloride and chlorhexidine, etc, adequate attention should be given.
Adverse Effects
Side effects of Sodium Hyaluronate :
>10%
Arthralgia (25%), Tenderness (61-92%), Swelling (81-91%), Firmness (88-89%), Bruising (52-87%), Pruritus (25-36%), Skin discoloration (33-78%), Firmness (86-89%), Lumps/bumps (56-83%)
1-10%
Increased blood pressure (4%), Fatigue (1%), Nausea (<2%), Injection site pain (3%), Paresthesia (1%), Tendonitis (2%), Limb pain (1%), Tendonitis (2%), Joint effusion (2%)
<1%
Angioedema, Arthritis, Herpetic eruptions, Thrombocytopenia, Peripheral edema, Vasovagal reaction, Hives, Gait disturbances
Mechanism of Action
Sodium hyaluronate is a polysaccharide which functions as a tissue lubricant. It is widely used in ophthalmic surgery because it forms a viscoelastic solution in water which makes it a suitable substitute for aqueous and vitreous humour.
Note
Vizol S 0.4% 0.004 Drops ophthalmic manufactured by JADRAN - GALENSKI LABORATORIJ D.D,. Its generic name is Sodium Hyaluronate. Vizol S 0.4% is availble in United Arab Emirates.
Farmaco UAE drug index information on Vizol S 0.4% Drops ophthalmic is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.
Some other brands of Sodium Hyaluronate :
Injection
Sportvis
10mg/ml
MDT INT'L SA
Injection / Intraarticular
Suplasyn 1-Shot
60mg/6ml
BIONICHE TEORANTA
Injection / Intraarticular
Suplasyn
10mg/ml
BIONICHE TEORANTA
Injection / Intraarticular
Synvisc Hylan G - F 20
10mg/ml
GENZYME BIOSURGERY
Injection / Intraarticular
Synvisc One Hyalan G-F 20
8mg/ml
GENZYME BIOSURGERY