Xalatan 0.005% Eye Drops (Solution)
Latanoprost 0.005% Eye prep
50mcg/ml
PFIZER MANUFACTURING BELGIUM N.V.
| Pack size | 2.5ml Dropper Bottle |
|---|---|
| Dispensing mode | POM |
| Source | BELGIUM |
| Agent | GULF DRUG EST. |
| Retail Price | 89.00 AED |
Indications
Xalatan 0.005% Eye Drops (Solution) is used for:
Open-angle glaucoma, Ocular HTN
Adult Dose
Adult:
As 0.005% eye drop:
Instill 1 drop in affected eye once daily in every evening.
Child Dose
Safety and efficacy not established
Renal Dose
Administration
Contra Indications
Hypersensitivity.
Precautions
Do not use within 5 min of thiomersal-containing preparations. Aphakia or pseudophakia with torn posterior lens cap or anterior chamber lenses; risk factors for cystoid macular oedema; brittle or severe asthma; history of intraocular inflammation; inflammatory, neovascular, angle-closure or congenital glaucoma; pregnancy, lactation. Remove contact lenses during use.
Lactation: not known whether distributed into milk; use with caution
Pregnancy-Lactation
Pregnancy
There are no adequate and well-controlled studies in pregnant women
Only use during pregnancy if potential benefits justifies potential risks to the fetus
Animal data
Reproduction studies performed in rats and rabbits. In rabbits, an incidence of 4 of 16 dams had no viable fetuses at a dose that was ~80 times the maximum human dose, and the highest nonembryocidal dose in rabbits was ~15 times the maximum human dose
Lactation
Not known whether distributed in milk; use caution
Interactions
Paradoxical elevations in IOP w/ other prostaglandins, prostaglandin analogs or prostaglandin derivatives.
Adverse Effects
Side effects of Latanoprost 0.005% Eye prep :
>10%
Increase in brown pigmentation of the iris (15.5%), Blurred vision (5-15%), Burning and stinging (5-15%), Foreign body sensation (5-15%), Itching (5-15%), Punctate epithelial keratopathy (5-15%), Conjunctival hyperemia (5-15%)
1-10%
Upper respiratory tract infection/cold/flu (4%), Dry eye (1-4%), Excessive tearing (1-4%), Eye pain (1-4%), Lid crusting (1-4%), Lid edema (1-4%), Lid erythema (1-4%), Lid discomfort/pain (1-4%), Photophobia (1-4%), Chest pain/angina pectoris (1-2%), Muscle/joint/back pain (1-2%), Rash/allergic skin reactions (1-2%)
<1%
Conjunctivitis, Diplopia, Discharge from the eye
Frequency Not Defined
Dizziness, Headache
Mechanism of Action
Latanoprost, a synthetic analogue of prostaglandin F2alpha, reduces the IOP by increasing the outflow of aqueous humour.
Note
Xalatan 0.005% 50mcg/ml Eye Drops (Solution) manufactured by PFIZER MANUFACTURING BELGIUM N.V.. Its generic name is Latanoprost 0.005% Eye prep. Xalatan 0.005% is availble in United Arab Emirates.
Farmaco UAE drug index information on Xalatan 0.005% Eye Drops (Solution) is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.